5 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
) Pathophysiology ... interferes with the activity ... and acute kidney injury ... also includes symptoms ... Toxicology #Diagnosis #Management
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings
 • Feeling a "pop"
 • Acute
Isolated Anterior Cruciate ... Ligament (ACL) Injury ... Inability to continue activity ... will be there + Lachman's ... #MSK #Sports #pathophysiology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
inflammation on skin -> Malar ... decr release and activity ... Manifestations #pathophysiology ... diagnosis #signs #symptoms ... #complications
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... Sex: female > male ... survival is 93-95% Pathophysiology ... increased B-cell activity ... Sarcoidosis #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... or triggers) is crucial ... Common Signs and Symptoms ... Pathophysiology ... absent NK-cell activity