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syndrome teg thromboelastogram thromboelastography activation behcet blood coagulation coagulopathy criticalcare dermatology erythematosus igg4 laboratory lupus macrophage mas normal phenotypes polychondritis
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Initial screening test ... with more severe disease ... #SLE #Summary #diagnosis ... #rheumatology # ... management
THROMBOELASTOGRAPHY (TEG) General Principle • A small cuvette is rotated to simulate sluggish venous flow and stimulate clot
formation • α - alpha angle ... - the angle tangent ... Thromboelastography #Diagnosis ... #Management #CriticalCare ... #Hematology #Interpretation
Thromboelastogram (TEG) Interpretation • R-time (R) - Time to first deviation from baseline • K-time (K)
Thromboelastogram (TEG) Interpretation ... (α) - Angle baseline ... thromboelastography #Interpretation ... #diagnosis #management ... #hematology #coagulopathy
Normal Thromboelastogram - Specific parameters represent the 3 phases of the cell-based model of haemostasis: initiation,
from start of test ... amplification -alpha = angle ... lysis time (s) #Diagnosis ... #Hematology #Coagulation ... #TEG #Normal #Interpretation
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Positive pathergy test ... is a skin prick test ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
highly inflammatory disease ... Liver function tests ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... specific laboratory tests ... IgG4 #Related #Disease ... #diagnosis #management ... workup #treatment #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blockers had the best ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
indirect Coombs test ... Graft Versus Host Disease ... Borrellia (Lyme disease ... #Transfusions #diagnosis ... #management #hematology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Sarcoidosis • Behcet disease ... /EGPA • RA Diagnosis ... : • Clinical tests ... Polychondritis #rheumatology ... #diagnosis #management
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