8 results
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
of Diabetic Ketoacidosis ... primary anabolic hormone ... counterregulatory hormones ... #Diabetic #Ketoacidosis ... #Endocrinology
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
Parathyroid Hormone ... (PTH) Effect in ... Calcium - Net Effect Hypercalcemia ... Calcium #Phosphorus #pathophysiology ... #endocrinology
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... of Diabetic Ketoacidosis ... - Type II DM pts ... #comparison #endocrinology ... #ketoacidosis #
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... Determine whether PTH-dependent ... Assess for non-hormonal ... Differential #Diagnosis #algorithm ... #endocrinology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Euglycemic Diabetic ... Ketoacidosis (EuDKA ... acidosis with pH ... level < 200 mg/dL Pathophysiology ... diagnosis #management #endocrinology
Hyperglycemic Crisis - Algorithm for DKA/HHS

Diagnostic criteria for DKA:
 • pH < 7.3
 • Anion gap
Hyperglycemic Crisis - Algorithm ... Hyperglycemic #Crisis #Algorithm ... #management #endocrinology ... #Diabetes #DM2 ... #Ketoacidosis
Hypercalcemia - Hormones and Pathophysiology  
Calcitriol:
 • Bones: Enhances mineralization
 • GI Tract: ↑ Ca2+
Hypercalcemia - ... Hormones and Pathophysiology ... Ca2+, ↑ PO4- PTH ... #Hormones #Pathophysiology ... #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... To prevent hypokalemia ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology ... #diabetes