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hematology diagnosis differential causes abnormal anticoagulation aptt doac hemostasis heparin models prolonged ptt thrombin warfarin anticoagulant anticoagulants apaxiban apixaban arterial
Coagulation cascade and anticoagulants Satyendra Dhar MD, @DharSaty #coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... @DharSaty #coagulation ... #coumadin #heparin ... thrombin #ptt #pt
Coagulation Cascade and Anticoagulant Sites of Action - Amy Chung, MD, MSc https://twitter.com/AmyChung #AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... AntiCoagulation #Cascade ... #Pharmacology #Pathophysiology ... Mechanisms #DOAC #Hematology
Coagulation Cascade Mnemonic - PITT vs PET PITT (with an I) = Intrinsic = APTT
Coagulation Cascade ... E)= Extrinsic=PT ... @pinoygastro #Coagulation ... #Cascade #Mnemonic ... PET #diagnosis #hematology
Hemostasis Physiology The blood's response to blood vessel injury can be viewed as four interrelated steps. Roman
numerals refer to coagulation ... #Hemostasis #Pathophysiology ... #Coagulation #Cascade ... #Hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... #Coagulation #Cascade ... thrombin #clot #PT ... #pathophysiology ... Rivaroxaban #Edoxaban #heparin
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... protein C and S Pathophysiology ... Fibrinogen: ↓ • PT ... 100mg/dL) - Heparin ... treatment #management #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
unfractionated heparin ... cause e.g. heparin ... intravascular coagulation ... #differential #hematology ... #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
for a Prolonged PT ... Pre-analytical cause (e.g. heparin ... thrombin inhibitors, heparin ... #differential #hematology ... #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... integrity Clotting cascade ... Acquired: • Heparin ... intravascular coagulation ... Differential #Diagnosis #Hematology
Review of the Coagulation Cascade Traditional Model: • Parallel extrinsic and intrinsic pathways. Contemporary Model: • 4 key
Review of the Coagulation ... Cascade Traditional ... #Cascade #diagnosis ... #models #hematology ... #pathophysiology
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