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diagnosis hematology management leukemia hemeonc lymphocytic algorithm cancer differentiation emergencies essential et lysis mds myelodysplasia myelodysplastic oncologic syndromes thrombocythemia tumor
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... smear: Blasts APML ... • Tumor lysis syndrome ... Transformation: • Complication ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... microglobulin Treatment ... #Chronic #Lymphocytic ... diagnosis #workup #oncology ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Pathophysiology ... • Induce blast cell ... #oncology
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... and AML) and solid ... malignancies Treatments ... #Tumor #Lysis #Syndrome ... #TLS #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... thrombocytopenia Complications ... uw_IMresidency #CLL ... #Leukemia #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... antibiotics TLS ... low Ca - q8 h TLS ... ± tocilizumab; call ... (~20 %) and APL
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology ... #oncology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
(ET) ET is a chronic ... , symptoms and complications ... generally requires all ... PV, MDS, CML) Treatment ... transformation into MDS or AML
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment ... Myelodysplastic syndromes ... of death from complications ... with repeated red cell
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