10 results
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
Late Budd-Chiari syndrome ... SAAG < 1.1: Biliary ... leak, Nephrotic syndrome ... albumin #gradient #hepatology ... #differential #
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
- Differential ... Infiltrative disease • Acute ... failure • Primary biliary ... #Differential # ... Diagnosis #Algorithm #Hepatology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Fitz-Hugh-Curtis syndrome ... Failure, Pancreatic, Biliary ... #Differential # ... Diagnosis #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... ATRA treatment Pathophysiology ... initiation • Differential ... #management #hematology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... of portal HTN: ascites ... • Cirrhosis/acute ... pregnancy • Primary biliary ... Diagnosis #causes #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... biliary obstruction ... , HELLP Syndrome ... Extrahepatic • Biliary ... #algorithm #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Gradient (SAAG) - Differential ... thrombosis (Budd-Chiari syndrome ... Veno-occlusive disease - Acute ... Tuberculosis - Biliary ... #Diagnosis #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Budd-Chiari syndrome ... fibrosis - Acute ... - Nephrotic syndrome ... Causes #diagnosis #differential ... #hepatology #SAAG
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... develops (DIC, ascites ... infiltration) Differential ... Liver #Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology