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diagnosis algorithm liver transaminitis hematology management obstetrics pregnancy aflp apml bandemia biliary causes cbc chemistry cholangitis cirrhosis differentiation elevated enzymes
Evaluation abnormal liver tests in pregnancy - Cholestatic Pattern - Hepatocellular Pattern #LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal ... Hepatocellular Pattern #LFTs ... transaminits #pregnancy #obgyn ... #obstetrics #hepatology ... #diagnosis #differential
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Burak @kwburak #LFTs ... #Elevated #Abnormal ... Algorithm #diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Levels: > 50x normal ... muscle 2-5x normal ... Liver #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... disease US — Normal ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Differential #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... infiltration) Differential ... Liver #Pregnancy #hepatology ... #obstetrics #obgyn ... diagnosis #management #pathophysiology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... initial response to abnormal ... #LFTs #Abnormal ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
) Differential ... • Abnormal temperature ... bacteremia • Abnormal ... #Bandemia #differential ... #pathophysiology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... - If both are normal ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... • ALT & AST normal ... • Bilirubin - Normal ... bile ducts Differential ... diagnosis #workup #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... 500 mg QD until normal ... diagnosis #management #hematology
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