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diagnosis hematology differential abnormal pt arterial bleeding bruising dic disseminated hemostasis intravascular management thrombosis treatment vascular venous
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... #Prolonged #Causes ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and aPTT If ... • Reduced liver ... #Prolonged #Causes ... #differential #hematology ... #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... protein C and S Pathophysiology ... DIC • Severe Liver ... Treat primary cause ... #diagnosis #causes
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Syndrome, Ischemic Liver ... intravascular coagulation ... and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... the PT remains prolonged ... intravascular coagulation ... discern these causes ... Differential #Diagnosis #Hematology
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