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diagnosis differential algorithm causes transaminitis abnormal cirrhosis hematology injury workup acute biliary chemistry cholangitis coagulation degenerative dic disorders disseminated elevated
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Cholangitis #pathophysiology ... #pbc #psc #hepatology ... #comparison
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Wilson's, HH, NAFLD ... 5x ULN - NAFLD ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Cholestatic disease ... Bile Ducts • PSC ... • Others #LFTs ... #Hepatology #LiverEnzymes
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Antitrypsin • Other: NAFLD ... Syndrome, Celiac Disease ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... Acute #algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hemochromatosis, Wilson's disease ... antitrypsin • Other: NAFLD ... HELLP, Celiac disease ... Differential #Diagnosis #hepatology ... Transaminitis #LFTs
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
a diagnosis of NAFLD ... body mass index; FBC ... disease; T2DM, ... #LFTs #Abnormal ... #Algorithm #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... cholestasis → Cirrhosis/Liver ... but elevated as disease ... or higher • Liver ... diagnosis #workup #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... of cholestatic disease ... disease: > 2 ... #differential #Hepatology ... transaminitis #LFTs
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
: INR/PT, aPTT(liver ... disease, decrease ... gastric bypass), LFT ... (liver disease) ... Causes #Workup #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... DIC • Severe Liver ... Disease: - Impaired ... hydration • RBC ... treatment #management #hematology
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