14 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... Morphology Microcytic RBC ... , Liver disease, ... Bite Cell RBC: G6PD ... Sickle Cell RBC
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... , Liver diseases ... , Liver diseases ... coagulopathy (DIC) #RBC ... #differential #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Neutrophils - Low RBC ... • Pancreatic Disease ... RBCs in Rouleaux ... Disease #Macrocytic ... Algorithm #Causes #Hematology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Antitrypsin • Other: NAFLD ... Syndrome, Celiac Disease ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... Acute #algorithm #hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... Defects, Drugs, Liver ... Disease, PNH ... 3) Internal (RBC ... Defects: Sickle cell anemia
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Biliary Cirrhosis (PBC ... ) - Summary PBC ... 30-65 years PBC ... Pathophysiology ... diagnosis #workup #hepatology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach to Anemia ... Spherocytosis, G6PD, PK, HbC ... Non-megaloblastic: Liver ... disease, Alcoholism ... Differential #Diagnosis #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
• Autoimmune diseases ... Even with normal WBC ... 21% had normal WBC ... #CBC #hematology ... #pathophysiology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
decreased PLT count: CBC ... disease, decrease ... changes), high MCV anemia ... disease), HBsAg ... /anti-HBc (rituximab