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diagnosis differential hematology management algorithm cirrhosis gastroenterology hyperbilirubinemia metabolism syndrome aflp alkaline alkphos alp arterial astalt biliary chemistry cholangitis coagulation
Bilirubin Metabolism - Pathophysiology • Conjugated Bilirubin • Unconjugated Bilirubin By Dr. Khushboo Gala @LouLectures #Bilirubin #Metabolism #Pathophysiology
Bilirubin Metabolism ... - Pathophysiology ... • Conjugated Bilirubin ... #Metabolism #Pathophysiology ... #hepatology #Liver
Drugs and Classes Associated with DILI and Type of Liver Injury #Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Drugs and Classes ... DILI and Type of Liver ... #LiverInjury #Hepatology ... #Pharmacology # ... Causes #DILI
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 Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... Phosphatase and Bilirubin ... initial insult Bilirubin ... ASTALT #AlkPhos #Bilirubin ... #Hepatology #Pathophysiology
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
non-ICU vs ICU causes ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct #bilirubin ... gastroenterology #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... hepatocellular injury • Bilirubin ... week • Direct bilirubin ... Elevation: • Bilirubin ... diagnosis #algorithm #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
function: INR, bilirubin ... Post-Hepatic: • Cardiac causes ... sarcoidosis) • Liver ... metastasis • Fatty liver ... #hepatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
of hemolysis or liver ... birth with serum bilirubin ... associated with bilirubin ... and stress may cause ... #hepatology #diagnosis
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... slightly elevated • Bilirubin ... or higher • Liver ... diagnosis #workup #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Syndrome, Ischemic Liver ... considered in all cases ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
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