15 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Differential Diagnosis: Infection ... Renal Failure Treatment ... diagnosis #management #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
pathogens, including PML ... Antimicrobial treatment ... status, and focal neurologic ... confusion, and focal neurologic ... InfectiousDiseases #Neurology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... early stages of infection ... Treatment: • HAART ... treatment • Cognitive ... dementia #AIDS #Neurology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Histoplasmosis Treatment ... Mucormycosis Treatment ... by culture or serology ... Aspergillosis Pathophysiology ... Diagnosis: • Serology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... response preceding infection ... Treatment: • Plasmapheresis ... diagnosis #management #treatment ... #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Preeclampsia, Eclampsia, Infection ... Etiology: • Pathophysiology ... Diagnosis: • Infection ... epilepticus Treatment
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
other causes of neurologic ... Precipitants: Infection ... noxious stimuli) TREATMENT ... Initiate empiric treatment ... #hepatology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
to a preceding infection ... • Most common infection ... the underlying pathophysiology ... and cauda equina TREATMENT ... diagnosis #management #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Direct microbial infection ... be ordered • Infectious ... Transverse Myelitis Treatment ... diagnosis #management #neurology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... microglobulin Treatment ... Transform to DLBCL, PML ... workup #oncology #hematology