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diagnosis treatment hematology abscess alkaline alp biliary cholangitis cirrhosis coagulation dic differential disseminated fatty hemophagocytic hlh hyophosphatasia intravascular leukostasis liver
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... = nonspecific (nausea ... Liver #Pregnancy #hepatology ... #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
in 1923 Low ALP ... Most cases diagnosed ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... obstruction • ALP ... diagnosis #workup #hepatology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Diagnosis and Management ... • Most common cause ... Lung Abscess Pathophysiology ... Coccidioides • Parasite ... #differential #causes
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... salmonella, ...), Parasites ... Drugs, Unknown cause ... 100 mg/m2) : in case ... Lymphohistiocytosis #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
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