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Langerhans cell histiocytosis presenting as a solitary jaw cyst. Classic reniform nuclei, prominent eosinophils, S100+, CD1A+,
Langerhans cell ... LisaRooperMD #Langerhans
On the left a case with multiple round and bizarre shaped cysts.
There was an upper lobe
is typical for Langerhans ... LangerhansCellHistiocytosis #Langerhans
Cystic versus Reticular
It can be difficult to determine whether we are dealing with a reticular pattern
a patient with Langerhans ... #Interstitial #Langerhans
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
Langerhans Cell ... proliferation of Langerhans ... examination showing Langerhans ... #LCH #Langerhans
On the left three different patients with lung cysts.
From left to right: Lymphangiomyomatosis, LIP and Langerhans
Lymphangiomyomatosis, LIP and Langerhans
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
bronchiolitis (RB-ILD) - Langerhans
The fourth pattern includes abnormalities that result in decreased lung attenuation or air-filled lesions.
These include:
- Emphysema
-
cysts (LAM, LIP, Langerhans
Granulomatous Lung Disease - Differential Diagnosis Algorithm
OP: organising pneumonia; EGPA: eosinophilic granulomatosis with polyangiitis; NSG: necrotising
PLCH: pulmonary Langerhans
Cystic Lung Disease
Upper Lobe Predominant: 
Langerhans Cell Histiocytosis, Pneumocystis Jiroveci, Hypersensitivity Pneumonitis, Neurofibromatosis Type 1, Paracoccidioidomycosis,
Predominant: Langerhans
Nodular pattern(2)
1. Sarcoidosis: nodules with perilymphatic distribution, along fissures, adenopathy.
2. TB: Tree-in-bud appearance in a patient
Langerhans cell