Langerhans cell histiocytosis presenting as a solitary jaw cyst. Classic reniform nuclei, prominent eosinophils, S100+, CD1A+, Langerin/CD207+. ~50% of LCH have BRAF V600E, ~25% have (mutually exclusive) MAP2K1 mutations. - Dr. Lisa Rooper @LisaRooperMD #Langerhans #cell #histiocytosis #Jaw #Pathology #Microscopy #Clinical
