20 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Thick ascending loop ... of Henle Gitelman ... Fanconi #Bartter #Gitelman ... #Localization #Nephron ... #Defects #Pathophysiology
Nephron Pathophysiology Study Guide 

- Proximal Tubule
- Loop of Henle
- Distal Tubule
- Collecting Duct

The Kidney Zone

#Nephron
Nephron Pathophysiology ... Proximal Tubule - Loop ... Kidney Zone #Nephron ... #Nephrology #Pathophysiology
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
Nephron Remodeling ... high doses of loop ... basis, the distal nephron ... of the distal nephron ... #Pathophysiology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... urearetics) 3) Loop ... Adenosine #Nephron ... #Pathophysiology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Acting on the Nephron ... mannitol) 3) Loop ... spironolactone) #Pathophysiology ... #Nephrology #Nephron
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... delivery to distal nephron ... #Syndrome #Pathophysiology
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... reabsorption in Proximal, loop ... distal component of Nephron ... absorption in distal nephron ... nephrology #Effects #pathophysiology
Approach to Elevated Bicarbonate (HCO3)
Risk Factors for Hypercapnea? (Hx of COPD, OSA, sedative use, CNS/muscular disorders?)
(+)
Remote Diuretics - Loop ... Recent Diuretics - Loop ... Barter, or Gitelman ... metabolic #alkalosis #algorithm
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... • HTN Absent: Loop ... Bartter syndrome, Gitelman ... Differential #Diagnosis #Algorithm
Pathophysiology of hypotonic hyponatremia

by Helbert Rondon, MD @NephroMD

#hypotonic #hyponatremia #nephrology #algorithm #Pathophysiology
Pathophysiology ... Helbert Rondon, MD @NephroMD ... hyponatremia #nephrology #algorithm ... #Pathophysiology