16 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Clinical Presentation ... Fever is the main clinical ... #Management #Hematology ... #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... ulceration • Ocular ... (Clinical Dx). ... #diagnosis #management ... signs #symptoms #rheumatology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Clinical Findings ... tissue site - Activation ... Renal (10-50%) - HTN ... nephrotic/nephritic syndrome ... arthritis (especially knees
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
of hands/feet, knees ... Ultrasound Diagnosis: CLINICAL ... history, exam and ... Arthritis #diagnosis #management ... #rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... Ocular- 50%: Ptosis ... weakness, arms > legs ... Clinical DX: - ... Gravis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... excessive macrophage activation ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
arthralgia, arm/leg ... Abdominal pain • HTN ... ocular inflammation ... purpura (lower legs ... Differential #Diagnosis #Rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... PRES-Associated Clinical ... • EEG: With persistent ... • Treatment of HTN ... #diagnosis #management
Ober's Test for TFL/ITB Inflammation

With the patient in the lateral position, affected side up.  The
slowly lowers the leg ... Test #Iliotibial #Band ... #Syndrome #ITBand ... #clinical #video ... #physicalexam #