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diagnosis hematology differential hemeonc pharmacology signs antiarrhythmics cardiotoxicity classes disorders hemophagocytic hlh hodgkins leukemia lymphohistiocytosis lymphoproliferative neurology rheumatology syndrome treatment
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... ) Classification ... #diagnosis #classification ... #hematology #oncology ... #management
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- B symptoms ... translocation • Types: Classification ... Nodal disease: B symptoms ... Diagnosis of B-Symptoms ... NonHodgkins #comparison #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphomas and Lymphoproliferative ... Algorithm Hodgkin Lymphoma ... pattern of spread, B symptoms ... Lymphoproliferative #Disorders #Classification ... #pathophysiology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
PTLD) Definition: Lymphoid ... Diagnosis and classification ... to 50% of PTLD cases ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... and secondary lymphoid ... Small lymphocytic lymphoma ... of large cell lymphoma ... Leukemia #Hematology #Oncology
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... improvement in symptoms ... heartfailure #diagnosis #management ... #cardiology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
lymphocytes, smudge cells ... to large cell lymphoma ... Constitutional symptoms ... Lymphocytic #Leukemia #oncology ... hemeonc #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Hodgkin, T-cell lymphoma ... , B-cell lymphoma ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... TLS #diagnosis #management
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Vaughan Williams Classification ... ++ influx into cells ... inotropy) ACCP Cardiology ... #Classes #pathophysiology ... #cardiology
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