26 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... mutated in all cells ... Retinoblastoma #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Persistent Pupillary Membrane (PPM) on Slit Lamp Ocular Examination

This membrane would be a remainder of the
tunica vasculosa lentis ... large enough to cause ... low vision or symptoms ... #PhysicalExam #clinical ... #video #ophthalmology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... diagnosis #management #hematology
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
the long bone or pelvis ... accounts for —9096 of cases ... Pathophysiology ... FES is a clinical ... Diagnosis #Signs #Symptoms
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... epidermis from dermis Clinical ... Signs/Symptoms/ ... - Erosions and crusts ... Diagnosis #Management #dermatology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Pathogenesis and clinical ... hyalinization causes ... #Retinopathy #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Pathogenesis and Clinical ... Viral replication causes ... vascular endothelial cells ... PolyarteritisNodosa #Pathophysiology ... Diagnosis #Signs #Symptoms
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Pathogenesis and Clinical ... diffusion of K+ out of cells ... may cause serum ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... renal failure Clinical ... Features: • Many symptoms ... patients have no symptoms
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... without other cause ... ARDS to explain symptoms ... transfusion • Pathophysiology