14 results
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
🔬Tumor cells are ... size lymphoid cells ... Prolymphocytes #Smear ... #Peripheral #Pathology ... #Microscopy #Clinical
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
lymphadenopathy • Blast cells ... Rapidly rising blast cells ... : Granulocytic cells ... organs When Cancer Cells ... Hypogammaglobulinemia, smudge cells
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Skin: - CLL cells ... • Peripheral smear ... : Smudge cells or ... basket cells can ... #diagnosis #workup
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Peripheral Smear ... • Hairy Cell Leukemia ... Workup: • Complete ... Peripheral blood smear
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... old, ~10,000 new cases ... transformation to acute leukemia ... #treatment #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... number of CD34+ cells ... number of CD34+ cells ... Number of CD34+ cells
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
Bell's Palsy - Diagnosis ... - Atypical Clinical ... No additional workup ... CNS inflammatory cause ... within 4m #Bells
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Peripheral smear ... lymphocytes, smudge cells ... immunophenotype Clinical ... #oncology #hematology ... hemeonc #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
promyelocytic leukemia ... organ damage Clinical ... • Peripheral smear ... Schistocytes, helmet cells ... #treatment #management