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diagnosis differential management clinical emergencies mds myelodysplastic oncologic radiology rheumatology anemia aplastic ascites cancer cmv computed ct cytomegalovirus dermatology functional
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... neutrophil count < 500 cells ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... old, ~10,000 new cases ... Management #treatment #hematology ... #oncology
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
CT or MRI scan of ... abdomen/pelvis ... • Cushing’s syndrome ... hyperparathyroidism • Congenital ... Mineralocorticoid excess syndromes
Causes of Primary and Functional Mitral Regurgitation (MR) Causes of primary mitral regurgitation - Rheumatic heart
prolapse (Marfan syndrome ... , Ehler-Danlos syndrome ... inferior wall - Congenital ... hypereosinophilic syndrome ... Differential #Diagnosis #Cardiology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
focal lesions on MRI ... Causes of false- ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... , Dyskeratosis congenita ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... cotrimoxazol • Congenital ... #diagnosis #hematology ... #oncology
Congenital Cytomegalovirus Infection- Ultrasonographic images showed ventricular dilatation in the fetal brain, and T2-weighted magnetic resonance
Congenital Cytomegalovirus ... Congenital CMV infection ... growth restriction, hematologic ... #clinical #NEJM ... #radiology #MRI
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO syndrome is ... Rule out other causes ... - MRI: inflammation ... , breast bone, pelvis ... #Rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
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