14 results
Bell's Phenomenon on Physical Exam

Carles Bell realized that when trying to close the eye on the
Physical Exam Carles ... #Phenomenon #Sign ... #clinical #video ... #PhysicalExam #ophthalmology ... #neurology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... epithelial basement membrane ... epidermis from dermis Clinical ... Signs/Symptoms/ ... - Erosions and crusts
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... Lysis of tumor cells ... diagnosis #management #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
across the plasma membrane ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
Pathogenesis and clinical ... of the tympanic membrane ... hearing loss, nausea ... #Mastoiditis #pathophysiology ... #signs #symptoms
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Pathogenesis and clinical ... anti-coagulation • Hematologic ... retinal edema caused ... #ophthalmology ... #diagnosis #signs
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... lateral sclerosis Pathophysiology ... cellular function Clinical ... - Causes progressive ... Lateral #Sclerosis #neurology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... Schistocytes, helmet cells ... Treat primary cause ... treatment #management #hematology
When to look for clonal/neoplastic hypereosinophilia (HEo)?
 - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
Exclusion of frequent causes ... ) - Clinical symptoms ... BM biopsy (Mast cells ... HEON #Diagnosis #Signs ... #Hematology #Workup
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... systemic sx + signs ... required +/- prompt ophthalmology ... GCA #Temporal #Signs