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diagnosis management differential arterial classification dermatologic dermatology embolism gpa granulomatosis hemeonc hemophagocytic hlh leukostasis lymphohistiocytosis lysis polyangiitis sjogrens tafro thrombocytopenia
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... • Goodpasture syndrome ... #rash #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... : • Behçet Syndrome ... • Cogan Syndrome ... differential #diagnosis #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... : • Pathophysiology ... Lysis of tumor cells ... diagnosis #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... coagulation and other causes ... 19 - PNH - Vasculitis ... Venous #Arterial #pathophysiology ... #hematology #differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Multinucleated giant cells ... , mucositis • Rash ... tract, and often causes ... • Cogan syndrome ... Differential #Diagnosis #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... : 2% Systemic Vasculitis ... #Rheumatology #
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
overgrowth of cells ... ANCA-associated vasculitis ... cell lymphoma Pathophysiology ... mature plasma cells ... diagnosis #management #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... caused by uncontrolled ... patients with the HLH syndrome ... Pathophysiology ... Diagnosis #Management #Hematology
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