22 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
causes development ... Particular CD4+ Th cells ... harmful -> Th Cells ... macrophages, mast cells ... #Immunology #pathophysiology
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... cell-mediated in > 90% of cases ... #Angioedema #Classification ... Diagnosis #Treatment #management ... #allergy
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... T-cells recruit ... reactions #types #allergy ... #table #classification
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Diagnosis and Management ... • Most common cause ... Lung Abscess Pathophysiology ... of PCN allergy ... #differential #causes
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... ++ influx into cells ... #Pharmacology #Classification ... #Classes #pathophysiology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Lymphoma (90-95% of cases ... ) Classification ... lymphoma #diagnosis #classification ... hematology #oncology #management
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... ICH Management ... = dilated BV = raises ... water leaves brain cells ... #neurosurgery #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T cells ... Phagocytosis of blood cells ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
increases out of cells ... Vaughan Williams Classification ... ++ influx into cells ... #Pharmacology #Classification ... #Classes #pathophysiology