17 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
causes development ... Particular CD4+ Th cells ... harmful -> Th Cells ... macrophages, mast cells ... #Immunology #pathophysiology
Bell's Palsy
Bell’s Palsy is a damage, acute weakness, or paralysis of the Facial nerve (7th CN),
Bell's Palsy Bell ... an identifiable cause ... The cause is unknown ... #Palsy #neurology ... #anatomy #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis
Bell's Phenomenon on Physical Exam

Carles Bell realized that when trying to close the eye on the
Bell's Phenomenon ... Physical Exam Carles ... neurologiabr #Bells ... #PhysicalExam #ophthalmology ... #neurology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... T-cells recruit ... reactions #types #allergy ... #table #classification
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... , asthenia • Neurologic ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Diagnosis Algorithm Cause ... intoxication Cause ... smooth muscle cells ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... ++ influx into cells ... #Pharmacology #Classification ... #Classes #pathophysiology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... = dilated BV = raises ... water leaves brain cells ... Pressure #ICP #Pathophysiology ... #neurology #neurosurgery
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
increases out of cells ... Vaughan Williams Classification ... ++ influx into cells ... #Pharmacology #Classification ... #Classes #pathophysiology