34 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
causes development ... Particular CD4+ Th cells ... harmful -> Th Cells ... macrophages, mast cells ... #Immunology #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... for secondary causes ... eosinophilia (common causes ... are asthma, allergy ... organ-specific signs or symptoms
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... T-cells recruit ... reactions #types #allergy ... #table #classification
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Retinoblastoma Signs / Symptoms ... Retinoblastoma #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Persistent Pupillary Membrane (PPM) on Slit Lamp Ocular Examination

This membrane would be a remainder of the
tunica vasculosa lentis ... large enough to cause ... low vision or symptoms ... clinical #video #ophthalmology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... (LP) tumour B cells ... pattern of spread, B symptoms ... Lymphoproliferative #Disorders #Classification ... #pathophysiology
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
the long bone or pelvis ... accounts for —9096 of cases ... Pathophysiology ... Diagnosis #Signs #Symptoms
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
some red blood cells ... 10,000 ft) • Symptoms ... • Signs/Symptoms ... • Signs/Symptoms ... • Pathophysiology
Hashitoxicosis

‘Leakage’ symptoms of active Hashimoto’s disease

- Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
Hashitoxicosis ‘Leakage’ symptoms ... thyroiditis that causes ... lymphocytes and plasma cells ... ‘Leakage’ symptoms ... Endocrinology #Diagnosis #Pathophysiology