18 results
Primary Bone Tumors - Differential Diagnosis Algorithm 

Metastatic - Most common tumour in adults
 - Breast
Primary Bone Tumors ... - Thyroid - Lung ... • Aneurysmal Bone ... Histiocytoma #Primary #Bone ... #Bony #Tumors #
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Granulomatous Disease ... Solid Tumors: Lung ... Miscellaneous - Bone ... Hyperthyroid, Bony ... #causes #endocrinology
Paget's Disease of Bone

 • Characterized by an ↑ rate of bone turnover with both excessive
of Bone • Characterized ... and formation of bone ... • Caused by ( ... , and long bones ... #management #treatment
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Tumours - See Bone ... - Skull/spine/Pelvis ... • Bone Marrow ... Fractures #Pathologic #MSK ... #Orthopedics #Causes
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Peripheral Vascular Disease ... bone) • Air Embolism ... • Dislocated Bone ... Vascular #JointPain #MSK ... #Orthopedics #Causes
Chronic Joint Pain - Differential Diagnosis Algorithm 
Intra-Articular
 - Bone
     • Stress
Intra-Articular - Bone ... Osgood-Schlatter Disease ... Ganglion Cyst - Bone ... Intraarticular #MSK ... #Orthopedics #Causes
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... Rule out other causes ... , breast bone, pelvis ... osteoarticular and skin disease ... Rheumatology #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, Biological + Bone ... /ml, ↑ LDH • Bone ... • Autoimmune diseases ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Bone Deformity / Limp - Differential Diagnosis Algorithm 
Infection
 • Septic Arthritis
 • Cortical Hypertrophy
 •
Bone Deformity / ... Differential Diagnosis Algorithm ... Arthritis Other Causes ... • Dwarfism #Bone ... Deformity #Limp #MSK
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... stimulates our body ... Too many cells in ... , this list is long ... As with many disease