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diagnosis hematology differential oncology orthopedics rheumatology syndrome hemophagocytic hlh lymphohistiocytosis anemia aplastic ascorbicacid bells cell cellulitis classification dermatology disease emergencies
Primary Bone Tumors - Differential Diagnosis Algorithm Metastatic - Most common tumour in adults - Breast
Primary Bone Tumors ... - Thyroid - Lung ... • Aneurysmal Bone ... Histiocytoma #Primary #Bone ... #Bony #Tumors #
Paget's Disease of Bone • Characterized by an ↑ rate of bone turnover with both excessive
Paget's Disease of Bone ... • Caused by ( ... , and long bones ... #diagnosis #management ... #treatment
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm Tumours - See Bone Lesions Scheme Paget's Disease -
Tumours - See Bone ... - Skull/spine/Pelvis ... Gastrointestinal Disease • Bone ... Fractures #Pathologic #MSK ... #Orthopedics #Causes
Vascular Joint Pain - Differential Diagnosis Algorithm - Constant Pain (Ischemia) - Acute Onset -
e.g. fractured long ... bone) • Air Embolism ... • Dislocated Bone ... Vascular #JointPain #MSK ... #Orthopedics #Causes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... old, ~10,000 new cases ... • Bone marrow ... only curative treatment ... #treatment #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... Rule out other causes ... , breast bone, pelvis ... and lower jaw Treatment ... Rheumatology #diagnosis #management
Emergency Management of Hyperkalemia in Adults Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach •
Emergency Management ... mmol/L - Consider cause ... Shift K+ into cells ... Remove K+ from body ... #algorithm #treatment
Orthopedic Emergencies Compartment Syndrome • An increase in compartment pressure to the point where tissue perfusion is
Syndrome • Syndrome caused ... bone fractures ... bone fractures ... including DM • Treatment ... #treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
= Hypocellular bone ... and petechiae Causes ... Hypoplastic MDS: • ↓ bone ... • Suggested by bone ... hypoplasia/fatty bone
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, Biological + Bone ... /ml, ↑ LDH • Bone ... Drugs, Unknown cause ... Treatment: • ... Lymphohistiocytosis #diagnosis #management
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