14 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Pathophysiology: • Cytokine ... Imaging: CXR- pulmonary ... #management #hematology ... #oncology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... increased B-cell activity ... → cytokines to ... renal failure Clinical ... Pulmonary: dyspnea
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
macrophages and T cells ... characteristic features Clinical ... Tuberculosis Diagnosis ... Tuberculosis #TB #Diagnosis ... #Management #Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... activation and cytokine ... absent NK cell activity ... #management #treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
macrophages and T cells ... characteristic features Clinical ... Tuberculosis Diagnosis ... Tuberculosis #TB #Diagnosis ... #Management #Treatment
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... “big & sticky” cells ... steroids, dialysis Cytokine-release ... renal failure, pulmonary ... #HemeOnc #Diagnosis
KSHV Inflammatory Cytokine Syndrome (KICS)
Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
KSHV Inflammatory Cytokine ... Syndrome (KICS) ... 3, and 4. 1) Clinical ... of KSHV viral activity ... #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... • PET scan - activity ... lymph node biopsy (diagnostic ... classification #hematology #oncology ... #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
ducts Clinical ... Disease: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... muscarinic agonists • Active ... #Management