8 results
hematology chronic cll hemeonc lymphocytic management signs centralretinalartery crao differentiation emergencies mds myelodysplasia myelodysplastic occlusion oncologic retinoblastoma syndrome syndromes workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... smear: Blasts APML ... Transformation: • Complication ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... phenomenon CLL Diagnosis ... • GI complications ... #diagnosis #workup ... #oncology #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... ATRA treatment Pathophysiology ... Release from blast cells ... : >3 symptoms, or ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... lymphocytes, smudge cells ... thrombocytopenia Complications ... #oncology #hematology ... #hemeonc #diagnosis
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... / Complications ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... Usually myeloid leukemias ... “big & sticky” cells ... (~20 %) and APL ... #HemeOnc #Diagnosis
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Disease: (i.e. leukemia ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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