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diagnosis hematology oncology algorithm causes hemolytic management morphology workup agglutinin aplastic blood bloodcell cancer classification disease elevatedmcv emergencies extravascular hemolysis
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Unstable hemoglobin disorders ... Cell Agglutinate: Cold ... , Paroxysmal cold ... #Morphology #differential ... #microscopy #atlas
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... #Morphology #Atlas ... key #diagnosis #differential ... #hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... the red blood cells ... involves production disorders ... that involves disorders ... These causes could
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Blood smear - RBC ... younger pts) Differential ... sensitize red blood cells ... (RBCs) at cold ... #hematology #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... practices that could ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... ITP, unexplained pancytopenia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Neutrophils - Low RBC ... • Small Bowel Disorder ... RBCs in Rouleaux ... Macrocytosis, Target Cells
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Pelger-Huet, Macrocytic anemia ... or λ), Smudge Cells ... bcr-able (+) ↑ WBC ... #hematology #Markers
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Algorithm • Sickle cells ... Agglutination - Cold ... membrane disorder
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
bone marrow + pancytopenia ... Anticonvulsants - Gold ... • Peripheral Pancytopenia ... : • ↓ RBC • ... #oncology #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(e.g. primary cold ... lymphoproliferative disorders ... • Intrinsic RBC ... Extravascular #Causes #differential ... #anemia
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