12 results
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential ... Malignancies 3. ... HLH syndrome 5. ... Acquired Aplastic Anemia
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential ... Malignancies 3. ... HLH syndrome 5 ... Acquired Aplastic Anemia
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... (2-48% depending ... Moderate > 2/3 and ... initiation • Differential ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
• M = F • 3 peaks ... : 1) Childhood 2) ... 15-25 years 3) ... Reticulocyte index < 2 ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... Agranulocytosis 3. ... • Richter’s Syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... #diagnosis #hematology ... #oncology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
to work through ... approach to the differential ... 2) Is ADH elevated ... demyelination syndrome ... #Differential #
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Hyperuricemia • Hyponatremia ... obstruction 3. ... kidney tubular cells ... output: 200 ml/hr 3.
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
symptoms in 1/3 ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... XR - ABVD x 2 ... #oncology #management
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Disease 3 ... Agglutinins (CAD) 2. ... Antibodies[PCH] 3. ... Cold Agglutinin Syndrome ... younger pts) Differential