14 results
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential ... Malignancies 3. ... HLH syndrome 5. ... Acquired Aplastic Anemia
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential ... Malignancies 3. ... HLH syndrome 5 ... Acquired Aplastic Anemia
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... (2-48% depending ... Triggers: ATRA treatment ... Moderate > 2/3 and ... initiation • Differential
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
to work through ... 2) Is ADH elevated ... demyelination syndrome ... #Differential # ... #management #nephrology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
• M = F • 3 peaks ... : 1) Childhood 2) ... 15-25 years 3) ... Reticulocyte index < 2 ... Treatment:
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... factor (GCSF) treatments ... Workup: • Complete ... blood count with differential ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... Agranulocytosis 3. ... microglobulin Treatment ... • Richter’s Syndrome ... Leukemia #diagnosis #workup
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Hyperuricemia • Hyponatremia ... obstruction 3. ... kidney tubular cells ... #nephrology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
3 times than men ... and pernicious anemia ... antibody that works ... Treatment: • ... #neurology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Disease 3 ... Agglutinins (CAD) 2. ... Antibodies[PCH] 3. ... Cold Agglutinin Syndrome ... younger pts) Differential