34 results
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... Syndrome - Diagnosis ... and Management ... #treatment #hematology ... #differential
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
CBC • Confirm: Flow ... microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... workup #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... Allogeneic stem cell ... only curative treatment ... #treatment #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... ~90% • Low Grade ... Responsive to Treatment ... growth, response to treatment ... pathophysiology #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
lymphocytes, smudge cells ... chemotherapy for low-risk ... uw_IMresidency #CLL ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis of tumor cells ... , Elevated Cr, Low ... calcium • Treatment ... TLS #diagnosis #management ... #hematology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel Syndrome ... Diagnosis and Management ... * Bloating not required ... for diagnosis Treatment ... Limited trial low
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... severe community-acquired ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
HPV, EBV), Renal cell ... (Goodpasture's syndrome ... Renal #Transplant #differential ... #blood #urine #management ... #treatment #nephrology