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diagnosis management hematology oncology rheumatology nephrology treatment causes monoclonal myelodysplastic acromegaly agglutinin algorithm als amyotrophic anemia arterial bcnie behcet blastomycosis
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... #differential # ... diagnosis #dermatology ... #oncology #clinical ... #skin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Rarely dominate the clinical ... reticularis Differential ... • Goodpasture syndrome ... vasculitis #Dermatologic
Ulcerative Blastomycosis Skin Lesion 57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
an old house & works ... heaped up borders); differential ... University Infectious Diseases ... Blastomycosis #SkinRash #dermatology ... #clinical #photo
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
- Differential ... of inflammatory cells ... SAPHO syndrome ( ... Sweet syndrome ... #Diagnosis #Dermatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... response to local skin ... injury) • Neurologic ... (Clinical Dx). ... ) Differential Diagnosis
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Diagnosis Neurologic-Centered ... capillary leak syndrome ... Ig deposition disease ... #Diagnosis #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... just beneath the skin ... Myeloproliferative Disease ... Workup: • Complete ... blood count with differential
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Approach to the differential ... hemolytic-uremic syndrome ... .2>5 red blood cells ... nose (epistaxis), skin ... #nephrology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Alpha & Mu) Skin ... et diutinum Neurologic ... thrombosis+Pulm HTN+skin ... #Monoclonal #Differential
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Hepatomegaly • Skin ... can indicate disease ... • Richter’s Syndrome ... Leukemia #diagnosis #workup
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