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diagnosis management differential ophthalmology algorithm gca vasculitis workup aion anteriorischemicopticneuropathy arteritis centralretinalartery chronic classification cll crao disorders eosinophil eosinophilia erythematosus
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... Eosinophilia, 500-1,500 cells ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
2) Typical symptoms ... • Cephalic symptoms ... Constitutional symptoms ... Doppler US : halo sign ... GiantCellArteritis #GCA #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Endocarditis, Aortic ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Optic Neuritis - ... caucasian • Symptoms ... Unilateral • Signs ... Alistair Baber #Optic ... Management #treatment #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... WBC >100k, + lab signs ... Lysis of tumor cells ... diagnosis #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Skin: - CLL cells ... or basket cells ... workup #oncology #hematology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
anti-coagulation • Hematologic ... Retina • Ganglion cells ... after CRAO -> Pale Optic ... ophthalmology #diagnosis #signs ... #symptoms
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
) - Clinical symptoms ... BM biopsy (Mast cells ... HEON #Diagnosis #Signs ... #Hematology #Workup
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... systemic sx + signs ... them, but urgent rheumatology ... GCA #Temporal #Signs ... #Symptoms #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
< 30 years - Aorta ... branches • GCA: - Aorta ... Presentation - Systemic Symptoms ... purpura: strong sign ... differential #diagnosis #rheumatology
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