19 results
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... Diagnosis Framework HEMATOLOGIC ... ONCOLOGIC EMERGENCIES ... neutrophil count < 500 cells ... STRUCTURAL ONCOLOGIC
Diagnostic criteria for Neutropenic Enterocolitis (NEC)
Major Criteria:
 • Neutropenia (ANC <500 x 10^9 cells/L)
 • Bowel
ANC <500 x 10^9 cells ... Diagnosis #criteria #hematology ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... Management #treatment #hematology ... #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Reed-Sternberg Cells ... Algorithm #Causes #Hematology ... #Oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
type (B cell, T cells ... natural killer (NK) cells ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
#Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... sub-types based on the hematologic ... marrow plasma cells ... #Significance #hematology ... #diagnosis #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
number of CD34+ cells ... number of CD34+ cells ... Number of CD34+ cells ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Skin: - CLL cells ... smear: Smudge cells ... or basket cells ... diagnosis #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
lymphocytes, smudge cells ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc