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diagnosis clinical leukemia management anemia chronic cll hemeonc lymphocytic myelodysplastic pathology acanthocytes aplastic blood cells emergencies interpretation mcleod myelodysplasia oncologic
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood Smear ... Analysis Hypochromia ... Peripheral #Blood #Smear ... #Analysis #hematology ... #microscopy #interpretation
A non-subtle example of true Sezary syndrome. Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
acanthocytes/spur cells ... patient with McLeod Syndrome ... Michael Moravek, MD ... #Smear #Pathology ... #Microscopy #Clinical
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... appear normal, but analysis ... Peripheral blood smear ... #diagnosis #hematology ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... #MDS #Diagnosis ... Management #treatment #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
(MDS) (normal or ... Hypocellular/Hypoplastic MDS ... abnormalities typical for MDS ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Peripheral smear ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... • Peripheral smear ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Peripheral smear ... lymphocytes, smudge cells ... Lauren Banaszak, MD ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... ): - Hematologic ... “big & sticky” cells ... denosumab, steroids, dialysis ... #Emergencies #Oncology
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