22 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... or basket cells ... • Neutropenia, anemia ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Cardiff COVID-19 Daily checklist - Matt Morgan
A daily checklist for critically ill #covid19 patients. Concentrates on
COVID-19 Daily checklist ... Morgan A daily checklist ... for critically ill ... COVID19 #Daily #criticalcare ... #SARSCoV2 #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
count (anemia) ... petechiae) • Frequent infections ... • Aplastic Anemia ... Megaloblastic Anemia ... • Parvovirus infection
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... Allogeneic stem cell
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... • Symptoms of anemia ... • hemolytic anemia ... malignancies -> CLL ... sensitize red blood cells
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Neutropenia - recurrent infections ... Constitutional Syndromes ... Idiopathic • Infections ... hematology #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... autoimmune hemolytic anemia ... and M panel Management ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... lymphocytes, smudge cells ... 5) Symptoms of anemia ... Complications: 1) Infection ... hemeonc #diagnosis #management
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Acute Retroviral Syndrome ... Acute Retroviral Syndrome ... Labs: • CD4+ T-cell ... decrease (<200 cells ... enzymes ↑ • Mild anemia