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diagnosis hematology covid19 hemeonc hemophagocytic hlh lymphohistiocytosis mds medications myelodysplastic oncology pharmacology siltuximab tocilizumab treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... Allogeneic stem cell
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19 IL-6 activates T cells and macrophages, among other cell types (see
-6 activates T cells ... Cytokine Activation Syndrome ... respiratory tract infection ... anti-IL6 mAb) #AntiIL6 ... #Pharmacology #Management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... with the HLH syndrome ... Triggers: ▪ Infections ... - Cytopenias (anemia ... underlying trigger: Infections
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