25 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... risk-stratification • Risks: infection ... Myelodysplastic #Syndrome ... treatment #hematology #oncology
Causes of Sudden Unexpected Death in Infancy (SUDI) - Differential Diagnosis Algorithm
Congenital Anomaly / Disorder:
 •
Neurologic Anomaly • Pulmonary ... Metabolic Disorders Infection ... Gastrointestinal infection ... Sudden Infant Death Syndrome ... #Causes #Peds #Pediatrics
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Neutropenia - recurrent infections ... Idiopathic • Infections ... Aplastic #Anemia #oncology ... hematology #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... Differential Diagnosis: Infection ... APML #diagnosis #management ... #hematology #oncology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
macrophages and T cells ... • Pulmonary fibrotic ... • HIV: 2/3 pulmonary ... Langerhans giant cells ... TB #Diagnosis #Management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... petechiae) • Frequent infections ... • Parvovirus infection ... diagnosis #hematology #oncology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
macrophages and T cells ... • Pulmonary fibrotic ... • HIV: 2/3 pulmonary ... Langerhans giant cells ... TB #Diagnosis #Management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Leukemia #Hematology #Oncology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... Renal Syndromes ... confirm DAH, r/o infection ... #Renal #Syndromes ... differential #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... or basket cells ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology