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diagnosis rheumatology treatment dermatology video differential leukemia bowel chronic clinical cll gastroenterology ibs iridodonesis iris irritable lymphocytic mds myelodysplastic ocular
Leser–Trélat Sign on Physical Exam Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy. #Leser
Leser–Trélat Sign ... paraneoplastic sign ... #PhysicalExam # ... #video #skin #dermatology ... #oncology
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 Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... Myelodysplastic #Syndrome ... #treatment #hematology ... #oncology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... neutrophil count < 500 cells ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome
Iridodonesis Physical examination revealed iridodonesis, or “dancing” of the iris, which was elicited by rapid movement of
movement, is a sign ... of ectopia lentis ... characteristic sign ... with Marfan’s syndrome ... Iris #SlitLamp #PhysicalExam
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 Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN) Nikolsky's sign is a clinical dermatological sign which is present
Nikolsky's Sign ... Stevens-Johnson Syndrome ... Staphylococcal scalded skin syndrome ... #TEN #Dermatology ... #PhysicalExam #
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 Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Diagnosis and Management ... Summary Clinical Signs ... marrow plasma cells ... Myeloma #Diagnosis #Management ... #oncology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... adsorption onto cancer cells ... vonWillebrand #Syndrome ... #treatment #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... WBC >100k, + lab signs ... Lysis of tumor cells ... TLS #diagnosis #management ... #hematology
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