11 results
A normal peripheral blood smear indicates the appropriate appearance of red blood cells, with a zone
smear indicates ... the size of the RBC ... #Clinical #Path ... #Microscopy #PeripheralBloodSmear ... #BloodSmear #Normal
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... She was diagnosed ... #Clinical #Path ... #BloodSmear #Blood ... #Smear #Microscopy
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Diagnosis Algorithm ... Normal Blood Smear ... Neutrophils - Low RBC ... RBCs in Rouleaux
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
- Differential ... Diagnosis Algorithm ... • Peripheral blood ... smear + DAT + further ... Hypochromic & microcytic RBCs
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... , Sudan Black, Auer ... Pelger-Huet, Macrocytic anemia ... or λ), Smudge Cells ... bcr-able (+) ↑ WBC
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... count with differential ... smear • Bone marrow ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... younger pts) Differential ... sensitize red blood ... cells (RBCs) at
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... Age: 50-60 • Auer ... - infiltrates (anemia ... Leukemia #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... • Peripheral smear ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... #workup #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... platelets - WBC ... Immunohistochemical studies (to differentiate ... classification #hematology #oncology