17 results
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
- Differential ... • Peripheral blood ... smear + DAT + further ... #Differential # ... Diagnosis #Algorithm #causes
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Volume (MCV) - Differential ... Algorithm Normal Blood ... Smear • Drugs ... Macrocytosis, Target Cells
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... age 70 years Symptoms ... Peripheral Smear ... count with differential ... smear • Bone marrow
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
• stored red blood ... - Sickle cell anemia ... Dissociation #Curve #Pathophysiology ... #Right #Shift #Differential ... #Causes #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... plateletcount), peripheral blood ... smear, HIV/HCV ... pylori test (GI symptoms ... changes), high MCV anemia
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
These cells can ... Crises can be precipitated ... The underlying pathophysiology ... of the baseline anaemia ... Features #Signs #Symptoms
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
SvO2 → Low PaO2 ANEMIC ... CYTOPATHIC HYPOXIA - Cells ... summary #pulmonary #differential ... #diagnosis #causes ... #pathophysiology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... younger pts) Differential ... sensitize red blood ... cells (RBCs) at
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... smear or on bone ... -> AML: Blast crises ... - infiltrates (anemia ... • Peripheral smear
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
Edema (NCPE) - Differential ... cells in the lung ... 10,000 ft) • Symptoms ... • Signs/Symptoms ... #differential #