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diagnosis management emergencies oncologic syndromes chronic classification cll differentiation hemeonc hodgkins leukemia lymphocytic lymphoma mds myelodysplasia myelodysplastic prs rheumatology syndrome
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... mononeuritis multiplex WORKUP ... : UA, Urine protein ... reveals increasing blood ... #differential #
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential ... Diagnosis Framework HEMATOLOGIC ... Hyperuricemia • Acute renal ... Vomiting, decreased urine ... diagnosis #cancer
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... Anaphylaxis, Acute Renal ... diagnosis #management #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... differential • ... Syndromes #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Lymphocytosis: Absolute blood ... Transform to DLBCL, PML ... Leukemia #diagnosis #workup ... #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Lymphoma Workup ... : • Full Blood ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... syndrome): - Hematologic ... , hypotension, renal ... failure, pulmonary
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... and renal abnormalities ... pulses, bruits, or blood ... Multinucleated giant cells ... (PR3-ANCA)): Microscopic
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