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hematology algorithm classification management pathophysiology acidosis aplastic curve dissociation elevatedmcv elevation fever hematuria hemolytic hodgkins hypoxemia hypoxia infectiousdiseases lactate lactic
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
- Differential ... Diagnosis Algorithm ... • Peripheral blood ... #Differential # ... #causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... abnormal under a microscope ... count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Oxyhemoglobin Dissociation Curve Left Shift - decreased unloading of O2 at tissue level (i.e. increased
• stored red blood ... cells - Hb variant ... - Sickle cell anemia ... #Right #Shift #Differential ... #Causes #Diagnosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... Normal Blood Smear ... Macrocytosis, Target Cells
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... - Differential ... Diagnosis Algorithm ... Red blood cells ... #Causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... and petechiae Causes ... result from low blood ... #oncology #hematology ... #diagnosis #management
Hypoxia and Hypoxemia - Overview Hypoxia - insufficient oxygen delivered to tissues to meet demands Hypoxemia - low
oxygen in the blood ... SvO2 → Low PaO2 ANEMIC ... CYTOPATHIC HYPOXIA - Cells ... summary #pulmonary #differential ... #diagnosis #causes
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Workup: • Full Blood ... Immunohistochemical studies (to differentiate ... classification #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... -> AML: Blast crises ... - infiltrates (anemia ... Leukemia #Hematology #Oncology ... #Diagnosis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... removal from the blood ... e.g., uptake by cells ... 30mmHg) - Severe anemia ... #Diagnosis #causes
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