17 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Sickled red cells ... #Peripheral #Blood ... Analysis #hematology #microscopy ... interpretation #clinical
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
• stored red blood ... cells - Hb variant ... - Sickle cell anemia ... Dissociation #Curve #Pathophysiology ... #Right #Shift #Differential
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... microangiopathic hemolytic anemia ... DIC is a clinical ... polychromatophilic cells ... Pathology #Smear #Microscopy
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cells, red blood ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope ... count with differential
A – cabot ring, B – Howell-Jolly Body

What are Cabot’s rings?
- They are delicate threadlike inclusions
cells in the peripheral ... blood of some patients ... /megaloblastic anaemia ... #Clinical #Pathology ... #Microscopy #BloodSmear
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
oxygen in the blood ... SvO2 → Low PaO2 ANEMIC ... CYTOPATHIC HYPOXIA - Cells ... summary #pulmonary #differential ... diagnosis #causes #pathophysiology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
pressure in the blood ... release from mast cells ... Medication #Causes #Differential ... #Pharmacology # ... Pathophysiology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... of peripheral blood ... cultures, including blood ... #differential # ... CBC #hematology #pathophysiology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Immunoglobulin M (IgM) • Blood ... younger pts) Differential ... sensitize red blood ... cells (RBCs) at
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
- Pathophysiology ... the Journal of Clinical ... reasoning during clinical ... Hospitalization #causes #pathophysiology ... #differential #