14 results
Diagnostic Criteria for Scleroderma Renal Crisis 

1. New onset blood pressure >150/85 mm Hg OR increase
Diagnostic Criteria ... Microangiopathic hemolytic anemia ... cells on urine ... microscopy - ... Renal #Crisis #Diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
- Differential Diagnosis ... • Peripheral blood ... History • Bite cells ... Recent travel/Fevers ... #Differential #Diagnosis
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... microangiopathic hemolytic anemia ... and laboratory diagnosis ... polychromatophilic cells ... Pathology #Smear #Microscopy
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cells, red blood ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope ... Myelodysplastic #Syndromes #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... Presentation: • Fever ... recurrent infections/fevers ... result from low blood ... oncology #hematology #diagnosis
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... She was diagnosed ... #Clinical #Path ... #BloodSmear #Blood ... #Smear #Microscopy
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... Pruritis after hot bath ... - infiltrates (anemia ... Lymphadenopathy • HSM • Fevers ... Hematology #Oncology #Diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
anemia • Cold ... Immunoglobulin M (IgM) • Blood ... sensitize red blood ... cells (RBCs) at ... Symptoms: High fevers
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Weight loss • Anemia ... Immune hemolytic anemia ... Workup: • Full Blood ... marrow biopsy - if blood
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... phenomenon CLL Diagnosis ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... Lymphocytic #Leukemia #diagnosis