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Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
another peripheral blood ... iron deficiency anemia ... Clinical #Path #Microscopy ... PeripheralBloodSmear #BloodSmear ... #Anemia #IronDeficiency
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
Dacrocytes (tear drop cells ... metaplasia, pernicious anemia ... some hemolytic anemias ... Clinical #Path #BloodSmear ... #Blood #Smear #
A normal peripheral blood smear indicates the appropriate appearance of red blood cells, with a zone
normal peripheral blood ... appearance of red blood ... cells, with a zone ... Clinical #Path #Microscopy ... PeripheralBloodSmear #BloodSmear
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Sickled red cells ... disease Bite cells ... #Peripheral #Blood ... Analysis #hematology #microscopy
A – cabot ring, B – Howell-Jolly Body

What are Cabot’s rings?
- They are delicate threadlike inclusions
cells in the peripheral ... blood of some patients ... /megaloblastic anaemia ... Clinical #Pathology #Microscopy ... #BloodSmear #CabotRings
Diagnostic Criteria for Scleroderma Renal Crisis 

1. New onset blood pressure >150/85 mm Hg OR increase
New onset blood ... Microangiopathic hemolytic anemia ... examination - Microscopic ... cells on urine ... microscopy -
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
) - Two target cells ... Target cells are ... with hemolytic anemias ... Clinical #Path #BloodSmear ... #Blood #Smear #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... abnormal under the microscope ... abnormal under a microscope ... marrow studies Treatment ... Immunosuppressive treatment
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Differential Diagnosis Algorithm ... • Peripheral blood ... History • Bite cells ... Deficiency • Sickle cells ... Differential #Diagnosis #Algorithm
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... seen in hemolytic anemias ... microangiopathic hemolytic anemia ... Clinical #Path #BloodSmear ... #Blood #Smear #