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diagnosis management causes differential nephrology ingestion toxicology classification crystals elevation gitelman hematology hyperkalemia hypertension hypokalemia k lactate lactic mds myelodysplasia
Toxic Alcohol Ingestion Alcoholic ketoacidosis - Methanol - Ethylene glycol - Isopropyl Alcohol • Metabolic Acidosis •
Toxic Alcohol Ingestion ... • Metabolic Acidosis ... Gap • Serum / Urine ... diagnosis #toxicology #comparison ... #table
Urine Microscopy Crystals Uric Acid crystals: - Formation promoted by acidic urine - Seen in tumor lysis
Urine Microscopy ... promoted by acidic urine ... in tumor lysis syndrome ... #Microscopy #Crystals ... #comparison #table
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
arsenic compounds, alcohol ... factor (GCSF) treatments ... abnormal under a microscope ... marrow studies Treatment ... Immunosuppressive treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... Weakness - Dark urine ... kidney tubular cells ... hour with goal urine ... per day until stable
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
test (with 24-h urine ... Polysomnography • Drug or alcohol ... scan of abdomen/pelvis ... • Cushing’s syndrome ... Screening #Workup #table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Redistribution: Acidosis ... lysis) ± Urine ... Elimination (see Table ... hyperchloremic acidosis ... Drives K+ into cells
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
excretion (e.g., urine ... e.g., uptake by cells ... before beginning treatment ... - Compartment syndrome ... Hypoglycemia - Alcohol
Toxic Alcohol Ingestion: Clinical Features, Diagnosis, and Management Methanol intoxication: • Accidental or intentional ingestion of adulterated
Toxic Alcohol Ingestion ... oxalate crystals in urine ... diagnosis #toxicology #comparison ... #table #management ... #treatment
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... apical membrane of cells ... Hypocalciuria (spot urine ... Renal tubular acidosis ... Rhabdomyolysis Treatment
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